Roland Klassen - Forschungsinformationssystem | Universität Kassel

Dr. Roland Klassen

Research Areas

Research Interest

Hefegenetik, non-conventional yeasts, Ribotoxine, tRNA Modifikation, tRNA Reparatur, DNA Reparatur, Mutagenese, DNA Polymerasen, Antimykotika

Academic background

10.1994-03.2000 Studium der Biologie (WWU Münster)

04.2000-10.2004 Promotion im Fachbereich Mikrobiologie (WWU Münster)

Projects as Principal Investigator

12/2015 - 11/2018

Publications

4 of 5

2012
2011
2011
2009	Klassen, R., Meinhardt, F., 2009. Yeast killer toxins: Fundamentals and applications, in: Anke T, W.D. (Eds. . (Hrsg.), The Mycota. Springer Verlag, Berlin Heidelberg, S. 107–130.
2008	Klassen, R., Fricke, J., Pfeiffer, A., Meinhardt, F., 2008. A modified DNA isolation protocol for obtaining pure RT-PCR grade RNA. Biotechnology Letters 30, 1041–1044.
2008	Klassen, R., Paluszynski, J., Meinhardt, F., 2008. Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker’s yeast. Microbiology 154, 3154–3164.Klassen, R., Meinhardt, F., 2007. Linear protein-primed replicating plasmids in eukaryotic microbes. In: Microbial linear plasmids, in: Meinhardt F, K.R. (Eds) (Hrsg.), Microbial linear plasmids. Springer Verlag, Berlin Heidelberg, S. 187–226.
2008	Klassen, R., Paluszynski, J., Wemhoff, S., Pfeiffer, A., Fricke, J., Meinhardt, F., 2008. The primary target of the killer toxin from Pichia acaciae is tRNA(Gln). Molecular Microbiology 69, 681–697.
2007	Jeske, S., Meinhardt, F., Klassen, R., 2007. Extranuclear Inheritance: Virus-like DNA-Elements in Yeast, in: Esser, K. (Hrsg.), Progress in Botany. Springer-Verlag, Berlin Heidelberg, S. 98–129.
2007	Klassen, R., Krampe, S., Meinhardt, F., 2007. Homologous recombination and the yKu70/80 complex exert opposite roles in resistance against the killer toxin from Pichia acaciae. DNA Repair 6, 1864–1875.
2007

Other Research Activities

2009	Post-Doc/Research Scientist I, UTMB (Texas, USA) Stay abroad
0	Additive actions of 5-fluorocytosine and fluconazole in resistant yeast strains Poster presentation
0	Additive actions of 5-fluorocytosine and fluconazole in resistant yeast strains Poster presentation
0	DNA repair pathways contribute to resistance against translational inhibitors in yeast Killer toxins of Kluyveromyces lactis and Pichia acaciae: mating inhibition and mating type control Poster presentation
0	Evidence for additional permeases involved in the toxicity of the antifungal agent 5-fluorocytosine (5-FC) in Saccharomyces cerevisiae Poster presentation
0	Poster presentation
0	Microbial linear plasmids. Microbiology Monographs, Vol. 7 (2007). Springer Verlag, Berlin Heidelberg Publisher activity
0	Novel yeast killer toxins mediate cell cycle arrest during S-phase and activation of the DNA damage checkpoint kinase Rad53 Poster presentation
0	The killer element pPin1-3 of the yeast Pichia inositovora. Poster Poster presentation
0	The Pichia acaciae killer system: Genetic analysis of toxin immunity Poster presentation