The article reports on a study conducted by the authors that analysed whether severe disabilities increased the likelihood of becoming unemployed during the first two years of the Covid-19 pandemic (2020 / 2021) and whether other relevant personal characteristics became targets of discriminatory processes (migration background, lack of vocational training, age, gender), and moderated the effect of severe disability on unemployment. The analyses were carried out using data from the German Labour Market and Social Security Panel (PASS) of the Institute for Employment Research. The findings showed that an officially recognised severe disability, the absence of a vocational training certificate, and a migration background significantly increased the likelihood of becoming unemployed during the pandemic. Apart from the effect of migration background, these findings were significant only for the year 2021, not the year 2020. In addition, an interaction effect between severe disabilities and migration background could be identified.